Take Action | Avoid Opioid SD
South Dakota Resource Hotline 1-800-920-4343

Learn about the risks.
Prescription opioids are highly addictive – always use with extreme caution.

Talk about it.
Talk to your doctor, your pharmacist, your children, and family and friends.

Reach out.
If you or someone you know is struggling, don’t wait. You just might save someone’s life.


How to prevent prescription opioid misuse and abuse:

Talk to your doctor about OTHER OPTIONS for pain relief that may work better and have fewer side effects.

STORE IN A SECURE PLACE – out of reach of children, family, friends, and visitors.

KEEP TRACK OF QUANTITIES: Knowing how many prescribed opioids have been taken – and how many remain in the bottle – will help you know if any have been taken by someone else.

Never take opioids with ALCOHOL or any other prescribed or over-the-counter MEDICATIONS. It can be a DEADLY combination.

NEVER MIX opioids with Benzodiazepines (Xanax or Valium), muscle relaxants (Soma or Flexeril), or hypnotics (Ambien or Lunesta).

Immediately return the bottle to a LOCKED CABINET OR OTHER SAFE PLACE after taking the prescribed dose of a prescription opioid.

Read and follow your prescription’s label directions carefully. NEVER TAKE MORE THAN PRESCRIBED.

NO LOOSE PILLS: Prescription opioids should only be kept in the bottle provided by your pharmacy.

TALK TO YOUR DOCTOR about other prescriptions, over-the-counter medications, or supplements you are taking.

Never SHARE OR SELL prescription opioids.

TALK TO YOUR CHILDREN, FAMILY, AND FRIENDS. Be sure they understand the serious risks and side effects of prescription opioids.


Here are some common signs that a prescription could be a problem:

  • When a person develops a tolerance – they need higher doses to relieve the same pain
  • When a person becomes physically dependent – they experience severe withdrawal symptoms when they stop taking the medication
  • When opioids are used incorrectly – mixed with alcohol, other prescriptions, or over-the-counter medications
  • When opioids are shared or given to others for pain or recreational use


If you are a healthcare provider, resources are available to help ensure your patients have access to safe & effective chronic pain treatment.

Scroll To Top