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Pharmacists play a critical role in preventing opioid deaths by increasing statewide access to naloxone.

As of October 1, 2020, South Dakota pharmacists with an active license can dispense naloxone under the statewide standing order to any eligible person who is at risk of an opioid-related overdose or able to assist an at-risk person (a family member or friend).

South Dakota pharmacists must complete the following requirements to participate.

7 Steps to Dispense Naloxone under the Statewide Standing Order

Click and jump to each step for further details.

Step 1: Print the Statewide Standing Order

Treat the standing order as you would any other prescription. Pharmacists should follow all usual steps as they would any other prescription, such as record keeping, documentation, billing, and labeling requirements.

The differences are:

  • Dr. Barnes (including NPI#) is listed as the prescriber for the medication
  • The Eligibility Assessment Form must be completed with the eligible individual before dispensing naloxone
  • You must provide printed educational material when counseling the patient (learn more in Step 5)

Participating pharmacies must keep a printed copy of the statewide standing order on premises.

Download and Print the Statewide Standing Order PDF

Step 2: Become a Participating Pharmacy

If your facility plans to dispense naloxone under the standing order, join the statewide participating pharmacy list by providing your pharmacy information to the SD Department of Social Services. This information will be used to generate a public list of pharmacies, making it easier for those seeking naloxone to obtain it. It will also allow us to contact your pharmacy should there be changes to the standing order.

Join the statewide Participating Pharmacy list

Step 3: Complete 1 Hour of Training

Pharmacies choosing to dispense naloxone under the statewide standing order must complete at least one hour of training related to naloxone dispensing and administration. Suitable trainings include, but are not limited to:

Any program that provides the pharmacist with at least one hour of naloxone education is sufficient.

Step 4: Print Eligibility Assessment Forms

Pharmacies must complete an Eligibility Assessment Form for every individual receiving naloxone.

Assessment forms must be:

  • Filled out with the eligible individual, before dispensing naloxone
  • Maintained with pharmacy records for at least two years
  • Be available for inspection and copying by the South Dakota Board of Pharmacy

Download and Print the Eligibility Assessment Form PDF

Step 5: Provide Patient Education

Patients who receive naloxone under the standing order must receive verbal and written education about:

  • Signs of an overdose
  • Overdose response steps
  • How to use naloxone

The SD Department of Social Services has developed Naloxone Brochures for pharmacy use. These brochures can be requested and shipped to your facility at no cost.

Order FREE Print Materials

Step 6: Submit Quarterly Reports

In order to save lives, a top priority for the SD Departments of Health and Social Services is to expand access to naloxone. Pharmacies play a huge role in helping us distribute and monitor the number of naloxone kits dispensed. The quarterly report form is quick and easy to fill out.

Reporting Periods:

  • January 1 – March 31
    Due April 30
  • April 1 – June 30
    Due July 31
  • July 1 – September 30
    Due October 31
  • October 1 – December 31
    Due January 31

Submit a Quarterly Report Form

Step 7: Submit Naloxone Reimbursement

Naloxone reimbursement is available for individuals without:

  • Insurance (including Medicaid) or a 3rd party payor source; or
  • The ability to pay due to financial circumstances

Review the full Naloxone Reimbursement Guidelines

Pharmacies seeking direct deposit of reimbursement must submit a substitute W-9.


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