South Dakota Opioid Resource Hotline 1-800-920-4343
Properly dispose of unused prescription medications

Find take back locations in your area:

Aberdeen
Aberdeen Police Department
114 2nd Ave. SE
Aberdeen, SD 57401-4201
Alexandria
Alexandria Sherriff’s Office
720 5th St.
Alexandria, SD 57311
Brandon
Brandon Police Department
304 Main Ave.
Brandon, SD 57005
Brookings
Brookings Sheriff’s Office
315 7th Ave.
Brookings, SD 57006
Canton
Canton Sheriff’s Office
128 N Main St. Suite 200
Canton, SD 57013-1708
Chamberlain
Lewis Family Drug
201 N. Main St.
Chamberlain, SD 57325
Custer
Custer Sheriff’s Office
420 Mount Rushmore Rd.
Custer, SD 57730-1934
De Smet
Lewis Family Drug
111 Calumet Ave. SE
De Smet, SD 57231
Elk Point
Elk Point Sheriff’s Office
209 E Main St. Ste. 250
Elk Point, SD 57025
Ellsworth Air Force Base
Ellsworth Air Force Base Hospital
1958 Scott Dr., Ste 4
Ellsworth Air Force Base, SD 57706
Flandreau
Flandreau Police Department
200 N Crescent St.
Flandreau, SD 57028
Huron
Huron Police Department
239 Wisconsin Ave. SW
Huron, SD 57350
Madison
Lewis Drug
741 S. Washington Ave.
Madison, SD 57042
Milbank
Lewis Family Drug
109 S. Main
Milbank, SD 57252
Mitchell
Mitchell Police Department
201 W 1st Avenue
Mitchell, SD 57301
Mitchell Sheriff’s Office
1015 S Miller Ave.
Mitchell, SD 57301
Mobridge
Mobridge Police Department
110 1st Ave. E
Mobridge, SD 57601
Pierre
Lynn’s Dakotamart
120 W Sioux Ave.
Pierre, SD 57501
Plankinton
Plankinton Sheriff’s Office
401 N Main St.
Plankinton, SD 57368
Rapid City
Rapid City Police Department
625 1st St., Evidence Building Lobby
Rapid City, SD 57701
Rapid City Police Department
300 Kansas City St., Public Safety Building Lobby
Rapid City, SD 57701
Walgreens
540 Mountain View Rd.
Rapid City, SD 57702
Sioux Falls
Lewis Drug
2901 S Minnesota Ave
Sioux Falls, SD 57105
Sioux Falls Police Department
320 W 4th St.
Sioux Falls, SD 57104
Sisseton
Coteau des Prairies Health Care System
205 Orchard Dr.
Sisseton, SD 57262
Spearfish
Spearfish Police Department
625 5th St.
Spearfish, SD 57783
Summerset
Summerset Police Department
7055 Leisure Lane
Summerset, SD 57718
Vermillion
Vermillion Police Department
15 Washington St.
Vermillion, SD 57069
Viborg
Lewis Family Drug
104 W Park Ave.
Viborg, SD 57070
Watertown
Watertown Sheriff’s Office
14 1st Ave SE
Watertown, SD 57201
Wessington Springs
Wessington Springs Sheriff’s Office
205 S. Wallace Ave.
Wessington Springs, SD 57382
Winner
Winner Police Department
217 E 3rd St.
Winner, SD 57580
Woonsocket
Woonsocket Sheriff’s Office
604 W 6th St.
Woonsocket, SD 57385
Yankton
Yankton Sheriff’s Office
410 Walnut St., Ste. 104
Yankton, SD 57078

Participate in the National Prescription Drug Take Back Events hosted by the DEA twice a year (April & October)
Purchase mail-back packages at participating retail pharmacies

If there isn’t a drop-off location in your community, many pharmacies offer mail-back envelopes for you to safely dispose of your unused medications through the U.S. Mail.

Visit the FDA for more information on proper prescription medication disposal