Take Back Sites | Avoid Opioid SD

South Dakota Opioid Resource Hotline 1-800-920-4343

Take Action > Take Back Sites

Properly dispose of unused prescription medications

Find take back locations in your area:

Aberdeen

Aberdeen Police Department

114 2nd Ave. SE
Aberdeen, SD 57401-4201

Alexandria

Hanson County Sheriff

720 5th St.
Alexandria, SD 57311

Beresford

Lewis Family Drug

911 W Cedar St , Ste. 1
Beresford, SD 57004

Bowdle

Turner Drug

3033 Main St.
Bowdle, SD 57428

Brandon

Brandon Police Department

304 Main Ave.
Brandon, SD 57005

Brookings

Brookings County Sheriff

315 7th Ave.
Brookings, SD 57006

Hy-Vee Pharmacy

790 22nd Ave. S
Brookings, SD 57006

Burke

Community Memorial Hospital

809 Jackson St.
Burke, SD 57523

Canton

Lewis Family Drug

715 E 5th St.
Canton, SD 57013

Lincoln County Sheriff

128 N Main St.
Canton, SD 57013

Chadron

Petersen Drug

302 Main St.
Chadron, NE 69337

Chamberlain

Lewis Family Drug

201 N Main St.
Chamberlain, SD 57325

Clark

Clark Police Department

120 N Commercial St.
Clark, SD 57225

Clear Lake

Lewis Family Drug

404 3rd Ave. S
Clear Lake, SD 57226

Corsica

Prairie Pharmacy

265 E Main St.
Corsica, SD 57328

Custer

Custer County Sheriff

420 Mount Rushmore Rd., Ste. 6
Custer, SD 57730

Custer Regional Hospital

1220 Montgomery St.
Custer, SD 57730

Dakota Dunes

Dunes Family Pharmacy

101 Tower Rd., Ste. 130
Dakota Dunes, SD 57049

De Smet

Lewis Family Drug

111 Calumet Ave. SE
De Smet, SD 57231

Deadwood

Lawrence County Sheriff

78 Sherman St.
Deadwood, SD 57732

Lead-Deadwood Regional Hospital

61 Charles St.
Deadwood, SD 57732

Eagle Butte

Cheyenne River Health Center/Eagle Butte Hospital

24276 166th St.
Eagle Butte, SD 57625

Elk Point

Union County Sheriff

209 E Main St., Ste. 250
Elk Point, SD 57025

Ellsworth Air Force Base

Ellsworth Air Force Base USAF-28 Medical Group/SGAL

2900 Doolittle Dr.
Ellsworth Air Force Base, SD 57706

Flandreau

Flandreau Police Department

200 N Crescent St.
Flandreau, SD 57028

Lewis Family Drug

127 E 2nd Ave.
Flandreau, SD 57028

Freeman

Heritage Pharmacy

609 S Hwy 81
Freeman, SD 57029

Gettysburg

Avera Gettysburg Hospital

606 E Garfield Ave.
Gettysburg, SD 57442

Potter County Sheriff

201 S Exene St.
Gettysburg, SD 57442

Hartford

Medicap Pharmacy

304 W Hwy 38, Ste. 102
Hartford, SD 57033

Hot Springs

Fall River Health Services Hospital

1201 Highway 71 S
Hot Springs, SD 57747

Huron

Huron Police Department

239 Wisconsin Ave. SW
Huron, SD 57350

Lewis Drug

1950 Dakota Ave. S
Huron, SD 57350

Lead

Lead Police Department

801 W Main St.
Lead, SD 57754

Madison

Lake County Sheriff

219 NE 1st St.
Madison, SD 57042

Lewis Drug

741 S Washington Ave.
Madison, SD 57042

Madison Police Department

116 W Center St.
Madison, SD 57042

Milbank

Bien Pharmacy

301 Flynn Dr., Ste. 2
Milbank, SD 57252

Lewis Family Drug

109 S Main St.
Milbank, SD 57252

Milbank Police Department

1001 E 4th Ave., #301
Milbank, SD 57252

Mitchell

Avera Grassland Pharmacy

1900 Grassland Dr., Ste. 101
Mitchell, SD 57301

Davison County Sheriff

1015 S Miller Ave.
Mitchell, SD 57301

Lewis Family Drug

1305 W Havens Ave.
Mitchell, SD 57301

Mitchell Department of Public Safety

201 W 1st Ave.
Mitchell, SD 57301

Mobridge

Family Pharmacy

1317 10th Ave. W
Mobridge, SD 57601

Mobridge Police Department

110 1st Ave. E
Mobridge, SD 57601

Pierre

Avera St. Mary’s Campus Pharmacy

100 Mac Lane, Ste. 101
Pierre, SD 57501

Lynn’s Dakotamart

120 W Sioux Ave.
Pierre, SD 57501

Pierre Police Department

3200 E SD Highway 34, Ste. 13
Pierre, SD 57501

Walgreen’s

100 E Sioux Ave.
Pierre, SD 57501

Plankinton

Aurora County Sheriff

401 N Main St.
Plankinton, SD 57368

Platte

Hoffman Drug

408 Main St.
Platte, SD 57369

Rapid City

Pennington County Sheriff & Rapid City Police Department

300 Kansas City St.
Rapid City, SD 57701

Rapid City Regional Hospital

353 Fairmont Blvd.
Rapid City, SD 57701

Sioux San Hospital

3200 Canyon Lake Dr.
Rapid City, SD 57702

The Medicine Shoppe

1304 Mt Rushmore Rd.
Rapid City, SD 57701

Walgreen’s

1902 Mt Rushmore Rd.
Rapid City, SD 57701

Walgreens

540 Mountain View Rd.
Rapid City, SD 57702

Redfield

Randall Pharmacy

1010 W 1st St., Ste. 2
Redfield, SD 57469

Spink County Sheriff

210 E. 7th Ave. #1
Redfield, SD 57469

Salem

Salem Community Drug

300 N Main St.
Salem, SD 57058

Scotland

Scotland Pharmacy

620 Billars St.
Scotland, SD 57059

Sioux Falls

Avera 69th Street Pharmacy

4400 W 69th St. , Ste. 300
Sioux Falls, SD 57108

Avera 7th Avenue Pharmacy

1200 S 7th Ave., Ste. 101
Sioux Falls, SD 57105

Avera McKennan Campus Pharmacy

1325 S Cliff Ave. , Ste. CP
Sioux Falls, SD 57105

Avera Specialty Pharmacy

1301 S Cliff Ave. , Ste. 200
Sioux Falls, SD 57105

Hy-Vee Pharmacy

1900 S Marion Rd.
Sioux Falls, SD 57106

Lewis Drug

4409 E 26th St
Sioux Falls, SD 57103

Lewis Drug Southgate

2901 S Minnesota Ave.
Sioux Falls, SD 57105

Sioux Falls Police Department

320 W 4th St.
Sioux Falls, SD 57104

Sisseton

Coteau des Prairies Hospital

205 Orchard Dr.
Sisseton, SD 57262

Woodrow Wilson Keeble Memorial Health Care Center

100 Lake Traverse Dr.
Sisseton, SD 57262

Spearfish

Spearfish Police Department

625 N 5th St.
Spearfish, SD 57783

Spearfish Regional Hospital

1440 N Main St.
Spearfish, SD 57783

Summerset

Summerset Police Department

7055 Leisure Lane, Ste. D
Summerset, SD 57718

Tyndall

Bon Homme Pharmacy

410 W 16th Ave.
Tyndall, SD 57066

Valentine

Shopko Pharmacy

525 E Highway 20
Valentine, NE 69201

Vermillion

Clay County Sheriff & Vermillion Police Department

15 Washington St.
Vermillion, SD 57069

Hy-Vee Pharmacy

525 W Cherry St.
Vermillion, SD 57069

Viborg

Lewis Family Drug

104 W Park Ave.
Viborg, SD 57070

Watertown

Codington County Sheriff

14 1st Ave. SE
Watertown, SD 57201

Hy-Vee Pharmacy

1320 9th Ave. SE
Watertown, SD 57201

Watertown Police Department

128 N Maple St.
Watertown, SD 57201

Webster

Cornwell Drug

701 Main St.
Webster, SD 57274

Wessington Springs

Jerauld County Sheriff

205 S Wallace Ave.
Wessington Springs, SD 57382

Winner

Winner Family Drug

745 E 8th St.
Winner, SD 57580

Winner Police Department

217 E 3rd St.
Winner, SD 57580

Woonsocket

Sanborn County Sheriff

604 W 6th St.
Woonsocket, SD 57385

Yankton

Hy-Vee Pharmacy

2100 Broadway Ave.
Yankton, SD 57078

Yankton County Sheriff

410 Walnut St., Ste. 104
Yankton, SD 57078

Participate in the National Prescription Drug Take Back Events hosted by the DEA twice a year (April & October)

Purchase mail-back packages at participating retail pharmacies

If there isn’t a drop-off location in your community, many pharmacies offer mail-back envelopes for you to safely dispose of your unused medications through the U.S. Mail.

Visit the FDA for more information on proper prescription medication disposal