Take Back Sites | Avoid Opioid SD

South Dakota Opioid Resource Hotline 1-800-920-4343

Take Action > Take Back Sites

Properly dispose of unused prescription medications

Find take back locations in your area:

Aberdeen

Aberdeen Police Department

114 2nd Ave. SE
Aberdeen, SD 57401-4201

Alexandria

Hanson County Sheriff

720 5th St.
Alexandria, SD 57311

Brandon

Brandon Police Department

304 Main Ave.
Brandon, SD 57005

Brookings

Brookings County Sheriff

315 7th Ave.
Brookings, SD 57006

Canton

Lincoln County Sheriff

128 N Main St.
Canton, SD 57013

Chadron

Petersen Drug

302 Main St.
Chadron, NE 69337

Chamberlain

Lewis Family Drug

201 N Main St.
Chamberlain, SD 57325

Custer

Custer County Sheriff

420 Mount Rushmore Rd., Ste. 6
Custer, SD 57730

De Smet

Lewis Family Drug

111 Calumet Ave. SE
De Smet, SD 57231

Eagle Butte

Cheyenne River Health Center/Eagle Butte Hospital

24276 166th St.
Eagle Butte, SD 57625

Elk Point

Union County Sheriff

209 E Main St., Ste. 250
Elk Point, SD 57025

Ellsworth Air Force Base

Ellsworth Air Force Base USAF-28 Medical Group/SGAL

2900 Doolittle Dr.
Ellsworth Air Force Base, SD 57706

Flandreau

Flandreau Police Department

200 N Crescent St.
Flandreau, SD 57028

Gettysburg

Potter County Sheriff

201 S Exene St.
Gettysburg, SD 57442

Hot Springs

Fall River Health Services Hospital

1201 Highway 71 S
Hot Springs, SD 57747

Huron

Huron Police Department

239 Wisconsin Ave. SW
Huron, SD 57350

Lead

Lead Police Department

801 W Main St.
Lead, SD 57754

Madison

Lewis Drug

741 S Washington Ave.
Madison, SD 57042

Madison Police Department

116 W Center St.
Madison, SD 57042

Milbank

Lewis Family Drug

109 S Main St.
Milbank, SD 57252

Mitchell

Davison County Sheriff

1015 S Miller Ave.
Mitchell, SD 57301

Mitchell Department of Public Safety

201 W 1st Ave.
Mitchell, SD 57301

Mobridge

Mobridge Police Department

110 1st Ave. E
Mobridge, SD 57601

Pierre

Lynn’s Dakotamart

120 W Sioux Ave.
Pierre, SD 57501

Pierre Police Department

3200 E SD Highway 34, Ste. 13
Pierre, SD 57501

Walgreen’s

100 E Sioux Ave.
Pierre, SD 57501

Plankinton

Aurora County Sheriff

401 N Main St.
Plankinton, SD 57368

Rapid City

Pennington County Sheriff & Rapid City Police Department

300 Kansas City St.
Rapid City, SD 57701

Sioux San Hospital

3200 Canyon Lake Dr.
Rapid City, SD 57702

Walgreen’s

1902 Mt Rushmore Rd.
Rapid City, SD 57701

Walgreens

540 Mountain View Rd.
Rapid City, SD 57702

Redfield

Randall Pharmacy

1010 W 1st St., Ste. 2
Redfield, SD 57469

Scotland

Scotland Pharmacy

620 Billars St.
Scotland, SD 57059

Sioux Falls

Lewis Drug Southgate

2901 S Minnesota Ave.
Sioux Falls, SD 57105

Sioux Falls Police Department

320 W 4th St.
Sioux Falls, SD 57104

Sisseton

Coteau des Prairies Hospital

205 Orchard Dr.
Sisseton, SD 57262

Woodrow Wilson Keeble Memorial Health Care Center

100 Lake Traverse Dr.
Sisseton, SD 57262

Spearfish

Spearfish Police Department

625 N 5th St.
Spearfish, SD 57783

Summerset

Summerset Police Department

7055 Leisure Lane, Ste. D
Summerset, SD 57718

Valentine

Shopko Pharmacy

525 E Highway 20
Valentine, NE 69201

Vermillion

Clay County Sheriff & Vermillion Police Department

15 Washington St.
Vermillion, SD 57069

Viborg

Lewis Family Drug

104 W Park Ave.
Viborg, SD 57070

Watertown

Codington County Sheriff

14 1st Ave. SE
Watertown, SD 57201

Webster

Cornwell Drug

701 Main St.
Webster, SD 57274

Wessington Springs

Jerauld County Sheriff

205 S Wallace Ave.
Wessington Springs, SD 57382

Winner

Winner Police Department

217 E 3rd St.
Winner, SD 57580

Woonsocket

Sanborn County Sheriff

604 W 6th St.
Woonsocket, SD 57385

Yankton

Yankton County Sheriff

410 Walnut St., Ste. 104
Yankton, SD 57078

Participate in the National Prescription Drug Take Back Events hosted by the DEA twice a year (April & October)

Purchase mail-back packages at participating retail pharmacies

If there isn’t a drop-off location in your community, many pharmacies offer mail-back envelopes for you to safely dispose of your unused medications through the U.S. Mail.

Visit the FDA for more information on proper prescription medication disposal